Using Freezerworks to manage a wildlife contraception center and biorepository
By Rick Michels Marketing Director, Freezerworks
For exotic and endangered wildlife, whether it be the giant panda, white rhino, mountain gorilla, or even the humble koala, fertility is our ally and great hope for species preservation. When such animals successfully mate in captivity and bear surviving offspring, we naturally celebrate. Such stories are so heartwarming and popular that we don’t often consider the other side of the equation: what does a zoo do to prevent a population explosion? Public service announcements remind us of the importance of having our pets neutered, so much so that it often seems this is the only form of animal birth control. But is it? Do tigers and lions utilize artificial contraception like humans do?
The answer is yes. Wildlife contraception is a lesser known but important part of wildlife management: whether that management takes place in a zoo, a natural park, or even in those rapidly shrinking open spaces. And just as humans remain concerned about health and safety issues as they relate to contraception, researchers who work in animal contraception are similarly concerned with the safety and efficacy of chemical based birth control. Continue reading “Biobanking, Zoology, and The Pill”→
Built on a 37-year history in apheresis collection, HemaCare Bioresearch Products and Services is a trusted research partner and leader in human primary cell and tissue collection, processing and cell therapy. Located in Van Nuys, California, HemaCare provides high-quality biological material derived from normal and mobilized peripheral blood, bone marrow and cord blood needed to ensure quality research outcomes that meet the unique needs of the scientific community.
As biomedical companies like HemaCare adapt to meet the growing needs of their customers, it is necessary to be flexible. For such companies operating in a heavily regulated environment, powerful yet configurable software can help meet these challenges and take advantage of new business opportunities. Today, Freezerworks’ sample management software plays an important role in managing the movement of blood products in a global market from production, storage, sale and shipment. And, because of Freezerworks’ configurable nature, HemaCare officials are now looking at ways to expand its use in a timely and seamless manner to meet those new opportunities. Continue reading “How HemaCare improved business productivity with Freezerworks”→
Lorrie Allen and Lauren Baber of the ITOR Biorepository, located in the Greenville Health System, Greenville, South Carolina
“To be an international destination center that develops and delivers innovative, personalized cancer therapies”
The above is the vision statement of the Institute for Translational Oncology Research (ITOR) of the Greenville Health System (GHS) of South Carolina, USA. To meet that vision, the institute requires a biorepository that works closely with both clinical and research departments. A biorepository may have valuable samples, perhaps the most valuable collection of rare and hard to acquire samples in the world. However, unless they are properly and fully annotated, those samples cannot be used to their maximum potential. An annotated, searchable, powerful database can provide rapid, invaluable molecular data for research and therapeutic uses. Continue reading “Freezerworks Advances Cancer Care with Effective Management of a Biorepository’s Clinical Data”→
Slee Mbhele is a Clinical Trial Data Manager for the University of Cape Town, Division of Medical Microbiology. The Division has multiple sample collection sites throughout Southern Africa, where it conducts up to 12 ongoing clinical trials, focusing on tuberculosis and childhood pneumonia. These trials are funded in part by the Bill and Melinda Gates Foundation, located in Seattle, Washington. The trial results are reported back to the foundation on a quarterly basis.
The College of American Pathologists (CAP) accreditation program for biorepositories is relatively new, having begun in 2012. The Genetic Resources Core Facility (GRCF) Biorepository and Cell Center at the Johns Hopkins School of Medicine recently became the twelfth biorepository accredited by CAP. According to its Director, Melissa Olson, PhD, the process, which she describes as a “major reorganizational effort”, was well worth it.
CAP accreditation, famous for its detailed checklists to ensure that quality policies and procedures are in place, offers for the biorepository “an overall outline to look at every aspect of this industry and make sure that all the pieces work together,” Olson said. And even though an inspection can sound like a way to ensure sleepless nights, the end result – standardization – is actually stress-reducing.
Saint Francis Hospital in Tulsa, Oklahoma has been using Freezerworks since 2002. Susan Arenson, a Medical Technologist at Saint Francis, has worked there for 31 years and began working with Freezerworks while she was the LIS Manager. Recently, she transitioned to the Information Technology team at Saint Francis, but was the main Medical Technologist during the transition to Freezerworks.
“Freezerworks has been a lifesaver for us, and we absolutely could not function without it.” – Susan Arenson, Medical Technologist/LIS Manager
The development of the Johns Hopkins Biological Repository (Director: Dr. Homayoon Farzadegan) is a remarkable story. More than one million frozen research samples were moved out of labs and hallways and into a state-of-the-art off-site biobank facility.
Stacey Cayetano and Brett Purinton shared the development of the Johns Hopkins repository and their use of Freezerworks Unlimited at our 2013 Users Meeting. Freezerworks Unlimited was configured by Stacey and Brett and the JHBR staff into a full featured (and affordable) Biorepository Information Management System, managing everything from testing and results to storage and shipping.
Their Powerpoint presentation can be viewed in PDF form here.
Dr. Angelique Corthals is the Scientific Director of the Tissue Bank at Stony Brook Hospital in New York. Prior to this, in 2000, she was instrumental in computerizing the biobank at the American Museum of Natural History. In both cases, she has installed Freezerworks.
Whether storing human or environmental samples, the Freezerworks advantage is configurability. As needs and methods change, configurability empowers the biobank staff to create, manage, update and maintain the data behind the collection of valuable specimens, while saving thousands of dollars in doing so.
Dr. Corthals presented a corporate workshop at the 2012 European, Middle Eastern & African Society for Biopreservation and Biobanking (ESBB) Conference in Granada. Click the link below to view a pdf of her PowerPoint presentation of the power and flexibility of Freezerworks in both human and environmental biobanking.
A Spotlight on the Laboratory of Cellular Physiology and Immunology at the Rockefeller University
By Rick Michels
June 7, 2013
“Perhaps my favorite thing about Freezerworks is that I spend less time working on weekends and more time with my wife and dogs.”James Pring
James Pring Co-Facilities Manager Steinman Lab at Rockefeller University
Founded by Nobel Laureate Dr. Ralph Steinman, the discoverer of dendritic cells, the Laboratory of Cellular Physiology and Immunology at the Rockefeller University in New York City works to further understand the nature of the immune system and how it relates to dendritic cells. In order to accomplish their goal of using this information to produce real-world benefits, researchers here are currently running a proof-of-concept trial that target antigens within antibodies of dendritic cells in vivo as well as 3 adjuvant trials.
James Pring, Senior Co-Facilities Manager of the Clinical Trials, is responsible for overseeing all clinical trial samples from the time they leave the patient until they enter the liquid nitrogen freezer and are sent out for research. With over tens of thousands sample aliquots and many collaborators, both domestic and international, the lab is constantly shipping and receiving samples. Pring appreciates the time and energy he saves with the Freezerworks Shipping Module. Continue reading “Nobel Prize Lab Uses Freezerworks to Manage Dendritic Cell Research”→
How the Freezerworks Unlimited® software design provides unique advantages in managing a biological repository for diabetes research
By Rick Michels February, 2007
Managing the process has the makings of a real logistical challenge: Enroll two thousand diabetes patients into clinical trials across the U.S. and Canada. From these patients, draw blood three to four times over the course of a number of years. From this blood, spin down and ship for storage in a centralized facility 24-38 vials of serum, plasma, cells and urine. Label and catalog these samples for distribution to a number of researchers so they can perform hundreds of tests in accordance with up to 12 protocols overall (at times 3-4 simultaneously).
Keep scrupulous track of the number of times a sample has been frozen and thawed prior to testing, as this is vital for ensuring standardized results and quality control of those hundreds of tests. All this is necessary for unlocking the keys to effective treatment for people living with diabetes, more than 18 million in the U.S. alone.
Overseeing this process, from collection to repository to dispersal, has been the primary work over the last six years of Marlene Brabham, Researcher Coordinator for the Medical University of South Carolina (MUSC) Division of Endocrinology, Diabetes and Medical Genetics. Brabham will be resigning her post at the end of January 2007. In her absence, assistant coordinator Erica Hood will continue running the operation of the repository. Dr. Maria Lopes-Virella serves as Principal Investigator. The sample data management backbone of the project is the software program Freezerworks Unlimited, from Dataworks Development. Continue reading “Diabetes Research: Freezer Inventory & Sample Tracking Case Study”→